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Read Article MLB picks today: Thursday's MLB best bets include Astros vs. Rangers play [5/28/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get MLB picks today and best bets for Thursday, May 28, 2026.
Today’s MLB picks for May 28, 2026 are here, with Astros vs. Rangers and Blue Jays vs. Orioles among the top plays identified by our model across Thursday’s MLB slate.
Dimers’ predictive analytics engine runs 24/7, searching the latest baseball odds to find legitimate betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of MLB best bets today [5/28, updated 6:05PM ET]
Below, you’ll find today’s best baseball bets, ranked by edge for Thursday, May 28, 2026.
Astros vs. Rangers over 7.5 runs (+120)
- Edge: 10.9%
- Probability: 56.4%
- Matchup: Astros vs. Rangers (8:05PM ET)
Our model has identified value on over 7.5 runs in Astros vs. Rangers at +120 odds. A 56.4% probability produces an edge of 10.9%, making this the strongest play for today's MLB slate.
Blue Jays vs. Orioles over 8.5 runs (+102)
- Edge: 6.7%
- Probability: 56.2%
- Matchup: Blue Jays vs. Orioles (6:35PM ET)
Blue Jays vs. Orioles over 8.5 runs carries a 6.7% edge and a probability of 56.2% at +102 odds, according to our model.
Cubs +1.5 (-130)
- Edge: 3.0%
- Probability: 59.5%
- Matchup: Cubs vs. Pirates (6:40PM ET)
Cubs +1.5 vs. Pirates at -130 odds shows a 3.0% edge, supported by a 59.5% probability in simulations.
Cubs ML (+160)
- Edge: 2.5%
- Probability: 40.6%
- Matchup: Cubs vs. Pirates (6:40PM ET)
A 2.5% edge and 40.6% probability make Cubs at the moneyline at a value play in the Cubs vs. Pirates matchup, per our model.
MLB best bets summary: Thursday, 5/28/2026
As of 6:05PM ET, here are our top MLB bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| Astros vs. Rangers | Over 7.5 Runs | +120 @ Kalshi | 10.9% | 56.4% |
| Blue Jays vs. Orioles | Over 8.5 Runs | +102 @ Kalshi | 6.7% | 56.2% |
| Cubs vs. Pirates | Cubs +1.5 | -130 @ Kalshi | 3.0% | 59.5% |
| Cubs vs. Pirates | Cubs ML | +160 @ Polymarket | 2.5% | 40.6% |
List of upcoming MLB games to bet on [5/28/2026]
- Blue Jays vs. Orioles (6:35PM ET, Thursday)
- Cubs vs. Pirates (6:40PM ET, Thursday)
- Astros vs. Rangers (8:05PM ET, Thursday)
Conclusion
Our MLB best bets are locked and loaded for May 28, 2026, featuring plays such as over 7.5 runs in the Astros vs. Rangers matchup and over 8.5 runs in the Blue Jays vs. Orioles matchup. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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