Pirates vs. Cubs prediction: Why Cubs are favored to win Sunday's MLB matchup [9/13/2026]

Using trusted machine learning and data analysis, we have re-simulated the outcome of Sunday's MLB game between the Pirates and Cubs, forming part of our MLB predictions coverage.

Our famous predictive model gives the Cubs a 57.5% chance of defeating the Pirates. According to our model, the Pirates (+1.5) have a 61.1% chance of covering the run line, while the over/under total of 6.5 runs has a 57.3% chance of going over.

Latest betting odds

We have sourced the best MLB odds in America for this game, which are listed here:

• Run Line: Pirates +1.5 (-178) / Cubs -1.5 (+178)
• Moneyline: Pirates +133, Cubs -130
• Total: Over/Under 6.5 (-108/+108)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Run line: Cubs -1.5 @ 36¢ via Novig
• Moneyline: Cubs @ 57¢ via Novig
• Total: Over 6.5 @ 52¢ via Novig

According to our MLB best bets, the top play to make on this game is Over 6.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first pitch details

Sunday's MLB matchup between the Cubs and Pirates at Wrigley Field is scheduled to commence at 2:20 PM ET.

• Who: Pittsburgh Pirates vs. Chicago Cubs
• Date: Sunday, September 13, 2026
• Time: 2:20 PM ET/11:20AM PT
• Venue: Wrigley Field

Conclusion

We predict the Cubs, with a 57.5% win probability, will likely beat the Pirates in Sunday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary MLB prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.