Pirates vs. White Sox prediction: Why Pittsburgh is favored to win Thursday's MLB matchup [9/10/2026]
Dimers' simulation model projects a 50.8% win probability for the Pirates at Rate Field.

The Chicago White Sox will square off with the Pittsburgh Pirates, in what is expected to be a tight MLB game, at Rate Field on Thursday, commencing at 7:40 PM ET.
The White Sox will start Hagen Smith (3-1, 0.56 ERA), while the Pirates have opted for Jared Jones (3-6, 4.46 ERA).
Dimers' advanced MLB model gives the Pirates a slight edge with a 50.8% win probability over the White Sox.
This article offers a complete Pirates vs. White Sox prediction, including best bets and picks.
Pirates vs. White Sox prediction and odds
Our leading predictive model currently gives the Pirates a 50.8% chance of beating the White Sox. According to our model, the White Sox (+1.5) have a 62.3% chance of covering the run line, while the 7.5-run over/under has a 55.3% chance of going over.
Latest betting odds
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Pirates -1.5 (+170) / White Sox +1.5 (-163)
- Moneyline: Pirates -104, White Sox +104
- Total: Over/Under 7.5 (-108/+104)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Pirates -1.5 @ 37¢ via Polymarket
- Moneyline: White Sox @ 49¢ via Novig
- Total: Over 7.5 @ 52¢ via Polymarket
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Thursday's MLB action between the White Sox and Pirates at Rate Field is scheduled to start at 7:40 PM ET.
- Who: Pittsburgh Pirates vs. Chicago White Sox
- Date: Thursday, September 10, 2026
- Time: 7:40 PM ET/4:40PM PT
- Venue: Rate Field
Conclusion
We predict the Pirates, with a 50.8% win probability, will likely beat the White Sox in Thursday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
This article's predictions and probabilities are generated by Dimers' proprietary MLB prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.




