Pirates vs. Padres prediction: San Diego favored to win Monday's MLB matchup [8/24/2026]
Get Pittsburgh Pirates vs San Diego Padres predictions for MLB Monday.

The San Diego Padres will take on the Pittsburgh Pirates, in what is expected to be a close MLB game, at Petco Park on Monday, beginning at 9:40 PM ET.
Robbie Ray (11-7, 3.20 ERA) will start for the Padres, up against Braxton Ashcraft (13-5, 3.68 ERA) for the Pirates.
Dimers' proven MLB model gives the Padres a slight edge with a 52.7% win probability over the Pirates.
This article offers a complete Pirates vs. Padres prediction, including best bets and picks.
For more, dive into Braxton Ashcraft's projected pitching stats.
Pirates vs. Padres prediction: Who will win and cover?
Our leading predictive model gives the Padres a 52.7% chance of defeating the Pirates.
According to our model, the Padres (+1.5) have a 64.1% chance of covering the run line, while the 7.5-run over/under has a 52.1% chance of going over.
Pirates vs. Padres odds [8/24/2026]
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Pirates -1.5 (+178) / Padres +1.5 (-180)
- Moneyline: Pirates +104, Padres -106
All odds are correct at the time of publication and are subject to change.
Pirates vs. Padres picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Pirates -1.5 @ +178 via DraftKings
- Moneyline: Padres @ -106 via Novig
- Total: Over 7.5 @ +108 via Novig
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Pirates vs. Padres game-day updates and essential details
Monday's MLB game between the Padres and Pirates at Petco Park is scheduled to commence at 9:40 PM ET.
- Who: Pittsburgh Pirates vs. San Diego Padres
- Date: Monday, August 24, 2026
- Time: 9:40 PM ET/6:40PM PT
- Venue: Petco Park
Conclusion
We predict the Padres, with a 52.7% win probability, will likely beat the Pirates in Monday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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