Mariners vs. Astros prediction: Seattle favored to win Monday's MLB matchup [5/11/2026]

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Written by Jason Bevilacqua

Get Seattle Mariners vs Houston Astros predictions for MLB Monday.

Seattle Mariners-Houston Astros Predictions and Game Preview.
Seattle Mariners vs. Houston Astros MLB prediction for Monday, May 11, 2026.

The Houston Astros will face the Seattle Mariners in MLB action at Daikin Park on Monday, starting at 8:10 PM ET.

Peter Lambert (2-2, 2.42 ERA) will be on the bump for the Astros, pitting him against George Kirby (4-2, 2.94 ERA) for the Mariners.

Based on updated simulations, Dimers' proven MLB model predicts the Mariners as the most likely winner of the Mariners vs. Astros game.

This article offers an expanded analysis of Monday's matchup, including best bets and picks.

Mariners vs. Astros prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Monday's MLB game between the Mariners and Astros, forming part of our MLB predictions coverage.

Our independent predictive model currently gives the Mariners a 56% chance of beating the Astros.

According to our model, the Astros (+1.5) have a 55% chance of covering the run line, while the over/under total of 8.5 runs has a 56% chance of going over.

 

Mariners vs. Astros odds [5/11/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Mariners Astros
Run Line -1.5 (+118) +1.5 (-131)
Moneyline -150 +130
Total o8.5 (-120) u8.5 (+100)

All odds are correct at the time of publication and are subject to change.

Mariners vs. Astros picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Mariners -1.5 +118
Moneyline Astros +130
Total Over 8.5 -120

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Mariners vs. Astros game-day updates and essential details

Monday's MLB matchup between the Astros and Mariners at Daikin Park is scheduled to start at 8:10 PM ET.

Conclusion

We predict the Mariners, with a 56% win probability, will likely beat the Astros in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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