Aug 18, 2026
Tigers vs. Pirates prediction: Why Pittsburgh is favored to win Tuesday's MLB matchup [8/18/2026]
Read Article Cardinals vs. Reds prediction: Why St. Louis is favored to win Tuesday's MLB matchup [8/18/2026]
Updated: | First published:
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Written by Dave Garofolo, Content Producer
Get St. Louis Cardinals vs Cincinnati Reds predictions for MLB Tuesday.
MLB action continues on Tuesday at 6:40 PM ET as the St. Louis Cardinals take on the Cincinnati Reds at Great American Ball Park.
Andrew Abbott (6-7, 4.13 ERA) will be the starting pitcher for the Reds, while the Cardinals will counter with Kyle Leahy (9-4, 3.38 ERA).
Dimers' advanced MLB model gives the Cardinals a slight edge with a 50.2% win probability over the Reds.
This article offers a complete Cardinals vs. Reds prediction, including best bets and picks.
Cardinals vs. Reds prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Tuesday's MLB matchup between the Cardinals and Reds, forming part of our MLB predictions coverage.
Our leading predictive model gives the Cardinals a 50.2% chance of beating the Reds.
According to our model, the Reds (+1.5) have a 61.9% chance of covering the run line, while the over/under total of 8.5 runs has a 54.1% chance of going over,.
Cardinals vs. Reds odds [8/18/2026]
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Cardinals -1.5 (+145) / Reds +1.5 (-147)
- Moneyline: Cardinals -113, Reds +111
All odds are correct at the time of publication and are subject to change.
Cardinals vs. Reds picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Reds +1.5 @ -147 via DraftKings
- Moneyline: Reds @ +111 via Novig
- Total: Over 8.5 @ -104 via Polymarket
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Cardinals vs. Reds game-day updates and essential details
Tuesday's MLB matchup between the Reds and Cardinals at Great American Ball Park is scheduled to commence at 6:40 PM ET.
- Who: St. Louis Cardinals vs. Cincinnati Reds
- Date: Tuesday, August 18, 2026
- Time: 6:40 PM ET/3:40PM PT
- Venue: Great American Ball Park
Conclusion
We predict the Cardinals, with a 50.2% win probability, will likely beat the Reds in Tuesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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