Southeast Missouri State vs. South Carolina prediction, odds, pick for Nov. 8, 2026

South Carolina is favored to beat Southeast Missouri State at Colonial Life Arena on Sunday (1:00 PM ET), according to Dimers' men's college basketball model.

Our Southeast Missouri State vs. South Carolina prediction gives the Redhawks a 92.1% chance of winning, but the latest odds suggest there's betting value on Southeast Missouri State to cover at +17.5.

Southeast Missouri State vs. South Carolina key predictions

• Predicted score: South Carolina 81-65 Southeast Missouri State
• South Carolina win probability: 92.1%
• Southeast Missouri State win probability: 7.9%
• Southeast Missouri State +17.5 spread: 53.8% cover probability
• Over 145.5 points: 52.0% probability

Our men's college basketball predictions project each team's final score using offensive and defensive efficiency, recent performance, long-term trends, and matchup-specific factors.

We calculate win, spread, and total probabilities based on these projections and historical CBB scoring patterns, then compare them with the latest odds to find betting value.

Southeast Missouri State vs. South Carolina odds

Here are the best available odds across the moneyline, spread, and total points markets we track.

• Southeast Missouri State moneyline: +1200 (DraftKings)
• South Carolina moneyline: -2400 (DraftKings)
• Southeast Missouri State +17.5: -106 (BetRivers)
• South Carolina -17.5: -105 (BetMGM)
• Over 145.5 points: -105 (BetMGM)
• Under 145.5 points: -105 (FanDuel)

Odds are subject to change and may vary by location.

Southeast Missouri State vs. South Carolina pick: Southeast Missouri State +17.5 (-106)

Our model makes South Carolina the likelier winner, but our best value bet is the Gamecocks to cover the +17.5 spread at -106 on BetRivers.

Those odds give Southeast Missouri State an implied cover probability of 51.5%, while our model puts it at 53.8%.

That's a 2.4% edge (accounting for rounding), the largest across the moneyline, spread, and total points markets for this game.

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Southeast Missouri State vs. South Carolina game details

• Matchup: Southeast Missouri State Redhawks vs. South Carolina Gamecocks
• Date: Sunday, November 8, 2026
• Time: 1:00 PM ET
• Venue: Colonial Life Arena

About this prediction

This preview uses predictions from our men's college basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

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