Alabama vs. LSU prediction favors LSU to win in college football Week 10 [2026]

Using powerful machine learning and data, we have re-simulated the outcome of Alabama vs. LSU, forming part of our college football predictions coverage.

Our famous predictive model currently gives LSU a 68.0% chance of defeating Alabama. Our predicted final score has LSU winning 30-24. According to our model, LSU (-4.5) has a 53.1% chance of covering the spread, while the over/under total of 52.5 points has a 53.6% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Alabama +4.5 (+117) / LSU -4.5 (-120)
• Moneyline: Alabama +199, LSU -203
• Total: Over/Under 52.5 (-115/+113)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Alabama +4.5 @ 46¢ via Novig
• Moneyline: LSU @ 67¢ via Novig
• Total: Over 52.5 @ 53¢ via Novig

According to our college football best bets, the top play to make on this game is LSU to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between LSU and Alabama at Tiger Stadium is scheduled to start at 3:30 PM ET.

• Who: Alabama vs. LSU
• Date: Saturday, November 7, 2026
• Time: 3:30 PM ET/12:30 PM PT
• Venue: Tiger Stadium

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Conclusion

We predict LSU, with a 68.0% win probability, will likely beat Alabama in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary college football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.