College football picks today: Week 1 Friday best bets include San Jose State vs. Eastern Michigan play [9/4/2026]

San Jose State +4.5 (-105)

• Edge: 12.4%
• Probability: 63.6%
• Matchup: San Jose State vs. Eastern Michigan (6:30PM ET)

Our model has identified value on San Jose State +4.5 at -105 odds. A 63.6% probability produces an edge of 12.4%, making this the strongest play for today's college football slate.

San Jose State ML (+165)

• Edge: 11.6%
• Probability: 49.4%
• Matchup: San Jose State vs. Eastern Michigan (6:30PM ET)

San Jose State ML carries a 11.6% edge and a probability of 49.4% at +165 odds, according to our model.

Indiana State vs. Purdue Under 57.5 points (-110)

• Edge: 8.3%
• Probability: 60.7%
• Matchup: Indiana State vs. Purdue (7:00PM ET)

Indiana State vs. Purdue Under 57.5 points at -110 odds shows a 8.3% edge, supported by a 60.7% probability in simulations.

Toledo vs. Michigan State under 49.5 points (-110)

• Edge: 6.4%
• Probability: 58.8%
• Matchup: Toledo vs. Michigan State (8:00PM ET)

A 6.4% edge and 58.8% probability make Toledo vs. Michigan State under 49.5 points a value play in the Toledo vs. Michigan State matchup, per our model.

Long Island University vs. Kansas Under 54.5 points (-108)

• Edge: 5.1%
• Probability: 57%
• Matchup: Long Island University vs. Kansas (8:00PM ET)

Long Island University vs. Kansas Under 54.5 points at -108 odds presents a 5.1% edge, with simulations resulting in a probability of 57%.

San Jose State vs. Eastern Michigan Under 56.5 points (-110)

• Edge: 3.8%
• Probability: 56.2%
• Matchup: San Jose State vs. Eastern Michigan (6:30PM ET)

Our model finds value on Under 56.5 points in San Jose State vs. Eastern Michigan at -110 odds, supported by an edge of 3.8%.

NCAAF best bets summary: Friday, 9/4/2026

As of 1:27AM ET, here are our top college football bets by edge recommended by our model:

List of upcoming college football games to bet on now

• San Jose State vs. Eastern Michigan (6:30PM ET, Friday)
• Indiana State vs. Purdue (7:00PM ET, Friday)
• North Carolina A&T vs. Georgia State (7:00PM ET, Friday)
• Toledo vs. Michigan State (8:00PM ET, Friday)
• Texas-El Paso vs. Oklahoma (8:00PM ET, Friday)
• Long Island University vs. Kansas (8:00PM ET, Friday)
• Fresno State vs. Southern California (9:00PM ET, Friday)
• Miami Florida vs. Stanford (9:00PM ET, Friday)

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Conclusion

Our college football best bets are locked and loaded for September 4, 2026, featuring plays such as San Jose State +4.5 vs. Eastern Michigan and San Jose State ML. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.