Duke vs. North Carolina State prediction favors Duke to win in college football Week 10 [2026]

Using trusted machine learning and data, we have re-simulated the result of Duke vs. North Carolina State, forming part of our college football predictions coverage.

Our leading predictive model gives Duke a 62.4% chance of beating North Carolina State. Our predicted final score has Duke winning 28-24. According to our model, North Carolina State (+5.5) has a 53.2% chance of covering the spread, while the over/under total of 49.5 points has a 56.7% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Duke -5.5 (+113) / North Carolina State +5.5 (-117)
• Moneyline: Duke -182, North Carolina State +178
• Total: Over/Under 49.5 (-141/+138)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Duke -5.5 @ 47¢ via Novig
• Moneyline: North Carolina State @ 36¢ via Novig
• Total: Under 49.5 @ 42¢ via Novig

According to our college football best bets, the top play to make on this game is North Carolina State to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between North Carolina State and Duke at Wayne Day Family Field at Carter-Finley Stadium is scheduled to commence at 12:30 PM ET.

• Who: Duke vs. North Carolina State
• Date: Saturday, November 7, 2026
• Time: 12:30 PM ET/9:30 AM PT
• Venue: Wayne Day Family Field at Carter-Finley Stadium

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Conclusion

We predict Duke, with a 62.4% win probability, will likely beat North Carolina State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary college football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.