Southeast Missouri State vs. Tennessee State prediction: Why Southeast Missouri State is favored to win in college football Week 10 [2026]

Using trusted machine learning and data, we have re-simulated the outcome of Southeast Missouri State vs. Tennessee State, forming part of our college football predictions coverage.

Our leading predictive model gives Southeast Missouri State a 79.0% chance of beating Tennessee State. Our predicted final score has Southeast Missouri State winning 29-19. According to our model, Tennessee State (+11.5) has a 54.3% chance of covering the spread, while the over/under total of 50.5 points has a 52.0% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Southeast Missouri State -11.5 (-113) / Tennessee State +11.5 (-110)
• Moneyline: Southeast Missouri State -413, Tennessee State +376
• Total: Over/Under 50.5 (-105/-104)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Tennessee State +11.5 @ -110 via DraftKings
• Moneyline: Tennessee State @ 21¢ via Novig
• Total: Under 50.5 @ -104 via BetRivers

According to our college football best bets, the top play to make on this game is Tennessee State +11.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between Tennessee State and Southeast Missouri State at Nissan Stadium is scheduled to begin at 3:30 PM ET.

• Who: Southeast Missouri State vs. Tennessee State
• Date: Saturday, November 7, 2026
• Time: 3:30 PM ET/12:30 PM PT
• Venue: Nissan Stadium

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Conclusion

We predict Southeast Missouri State, with a 79.0% win probability, will likely beat Tennessee State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary college football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.