South Carolina State vs. Bethune-Cookman prediction favors South Carolina State to win in college football Week 4 [2026]

Using trusted machine learning and data, we have re-simulated the outcome of South Carolina State vs. Bethune-Cookman, forming part of our college football predictions coverage.

Our independent predictive model currently gives South Carolina State an 88.4% chance of beating Bethune-Cookman. Our predicted final score has South Carolina State winning 36-21. According to our model, Bethune-Cookman (+16.5) has a 51.7% chance of covering the spread, while the 57.5-point over/under has a 51.2% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: South Carolina State -16.5 (-110) / Bethune-Cookman +16.5 (-110)
• Moneyline: South Carolina State -950, Bethune-Cookman +600
• Total: Over/Under 57.5 (-105/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Bethune-Cookman +16.5 @ -110 via bet365
• Moneyline: South Carolina State @ -950 via bet365
• Total: Over 57.5 @ -105 via Caesars

According to our college football best bets, the top play to make on this game is Over 57.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Bethune-Cookman and South Carolina State at Daytona Stadium is scheduled to start at 7:00 PM ET.

• Who: South Carolina State vs. Bethune-Cookman
• Date: Saturday, September 26, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Daytona Stadium

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Conclusion

We predict South Carolina State, with an 88.4% win probability, will likely beat Bethune-Cookman in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.