Blue Jays vs. Astros prediction: Houston favored to win Wednesday's MLB matchup [8/5/2026]
Get Toronto Blue Jays vs Houston Astros predictions for MLB Wednesday.

MLB action continues on Wednesday at 2:10 PM ET as the Toronto Blue Jays square off with the Houston Astros at Daikin Park.
Hunter Brown (3-1, 3.42 ERA) will get the ball for the Astros, while the Blue Jays are going with Jameson Taillon (2-6, 5.92 ERA).
Dimers' proven MLB model projects the Astros as the most likely winner in this Blue Jays vs. Astros prediction.
This article offers an expanded analysis of Wednesday's matchup, including best bets and picks.
Blue Jays vs. Astros prediction: Who will win and cover?
Our famous predictive model gives the Astros a 61.7% chance of beating the Blue Jays.
According to our model, the Blue Jays (+1.5) have a 54.9% chance of covering the run line, while the over/under total of 8.5 runs has a 51.1% chance of going over,.
Blue Jays vs. Astros odds [8/5/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Blue Jays | Astros |
|---|---|---|
| Run Line | +1.5 (-133) | -1.5 (+128) |
| Moneyline | +163 | -163 |
| Total | o8.5 (+113) | u8.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Blue Jays vs. Astros picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Astros -1.5 | +128 |
| Moneyline | Blue Jays | +163 |
| Total | Over 8.5 | +113 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Blue Jays vs. Astros game-day updates and essential details
Wednesday's MLB game between the Astros and Blue Jays at Daikin Park is scheduled to commence at 2:10 PM ET.
- Who: Toronto Blue Jays vs. Houston Astros
- Date: Wednesday, August 5, 2026
- Time: 2:10 PM ET/11:10AM PT
- Venue: Daikin Park
Conclusion
We predict the Astros, with a 61.7% win probability, will likely beat the Blue Jays in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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