MLB picks today: Thursday's MLB best bets include Rays vs. Yankees play [9/24/2026]

Rays vs. Yankees Over 6.5 runs (-104)

• Edge: 9.2%
• Probability: 60.2%
• Matchup: Rays vs. Yankees (7:05PM ET)

Our model has identified value on Over 6.5 runs in Rays vs. Yankees at 51¢ odds. A 60.2% probability produces an edge of 9.2%, making this the strongest play for today's MLB slate.

Diamondbacks vs. Rockies Over 10.5 runs (+108)

• Edge: 7.3%
• Probability: 55.4%
• Matchup: Diamondbacks vs. Rockies (3:10PM ET)

Diamondbacks vs. Rockies over 10.5 runs carries a 7.3% edge and a probability of 55.4% at 48¢ odds, according to our model.

Reds vs. Braves Over 7.5 runs (-104)

• Edge: 6.8%
• Probability: 57.8%
• Matchup: Reds vs. Braves (7:15PM ET)

Reds vs. Braves Over 7.5 runs at 51¢ odds shows a 6.8% edge, supported by a 57.8% probability in simulations.

Marlins vs. Cubs over 7.5 runs (+102)

• Edge: 5.6%
• Probability: 55.1%
• Matchup: Marlins vs. Cubs (2:20PM ET)

A 5.6% edge and 55.1% probability make Marlins vs. Cubs over 7.5 runs a value play in the Marlins vs. Cubs matchup, per our model.

Guardians vs. Red Sox Over 7.5 runs (+104)

• Edge: 5.2%
• Probability: 54.2%
• Matchup: Guardians vs. Red Sox (6:45PM ET)

Guardians vs. Red Sox Over 7.5 runs at 49¢ presents a 5.2% edge, with simulations resulting in a probability of 54.2%.

Padres vs. Dodgers Over 7.5 runs (+100)

• Edge: 4.2%
• Probability: 54.2%
• Matchup: Padres vs. Dodgers (10:10PM ET)

Our model finds value on Over 7.5 runs in Padres vs. Dodgers at 50¢, supported by an edge of 4.2%.

Brewers vs. Phillies Over 8.5 runs (+104)

• Edge: 3.8%
• Probability: 52.8%
• Matchup: Brewers vs. Phillies (6:05PM ET)

Our model has uncovered value on Brewers vs. Phillies Over 8.5 runs at 49¢. A 52.8% probability produces a 3.8% edge, making this a strong play for today's MLB action.

Mets vs. Rangers Over 8.5 runs (+100)

• Edge: 3.3%
• Probability: 53.3%
• Matchup: Mets vs. Rangers (2:35PM ET)

A 3.3% edge on a 53.3% probability makes Over 8.5 runs at +100a solid value play in today's Mets vs. Rangers matchup.

Athletics ML (+156)

• Edge: 3.2%
• Probability: 42.3%
• Matchup: Astros vs. Athletics (9:40PM ET)

Our model projects value on Athletics to win at 39¢. A 42.3% probability produces a 3.2% edge, making Athletics the favorable ML play in today's matchup.

Reds ML (+208)

• Edge: 3.1%
• Probability: 35.5%
• Matchup: Reds vs. Braves (7:15PM ET)

Rounding out our top 10 bets, Reds to defeat Braves at 32¢ shows a 35.5% probability and a 3.1% edge.

MLB best bets summary: Thursday, 9/24/2026

As of 5:03AM ET, here are our top MLB bets by edge recommended by our model:

List of upcoming MLB games to bet on [9/24/2026]

• Cardinals vs. Pirates (12:35PM ET, Thursday)
• White Sox vs. Royals (2:10PM ET, Thursday)
• Marlins vs. Cubs (2:20PM ET, Thursday)
• Mets vs. Rangers (2:35PM ET, Thursday)
• D-Backs vs. Rockies (3:10PM ET, Thursday)
• Brewers vs. Phillies (6:05PM ET, Thursday)
• Guardians vs. Red Sox (6:45PM ET, Thursday)
• Rays vs. Yankees (7:05PM ET, Thursday)
• Reds vs. Braves (7:15PM ET, Thursday)
• Angels vs. Mariners (9:40PM ET, Thursday)
• Astros vs. Athletics (9:40PM ET, Thursday)
• Padres vs. Dodgers (10:10PM ET, Thursday)

Conclusion

Our MLB best bets are locked and loaded for September 24, 2026, featuring plays such as over 6.5 runs in the Rays vs. Yankees matchup and over 10.5 runs in the Diamondbacks vs. Rockies matchup. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.