MLB picks today: Saturday's MLB best bets include Reds vs. Blue Jays play [9/26/2026]

Reds vs. Blue Jays Over 7.5 runs (-115)

• Edge: 5.4%
• Probability: 58.9%
• Matchup: Reds vs. Blue Jays (3:07PM ET)

Our model has identified value on Over 7.5 runs in Reds vs. Blue Jays at 53¢ odds. A 58.9% probability produces an edge of 5.4%, making this the strongest play for today's MLB slate.

Dodgers vs. Giants Over 7.5 runs (+106)

• Edge: 5.1%
• Probability: 53.7%
• Matchup: Dodgers vs. Giants (4:05PM ET)

Dodgers vs. Giants over 7.5 runs carries a 5.1% edge and a probability of 53.7% at +106 odds, according to our model.

Rockies vs. White Sox Over 8.5 runs (+108)

• Edge: 5.0%
• Probability: 53.1%
• Matchup: Rockies vs. White Sox (7:10PM ET)

Rockies vs. White Sox Over 8.5 runs at 48¢ odds shows a 5.0% edge, supported by a 53.1% probability in simulations.

Cardinals vs. Brewers over 7.5 runs (-106)

• Edge: 4.3%
• Probability: 55.7%
• Matchup: Cardinals vs. Brewers (7:10PM ET)

A 4.3% edge and 55.7% probability make Cardinals vs. Brewers over 7.5 runs a value play in the Cardinals vs. Brewers matchup, per our model.

Braves vs. Marlins Over 8.5 runs (-106)

• Edge: 3.9%
• Probability: 55.3%
• Matchup: Braves vs. Marlins (4:10PM ET)

Braves vs. Marlins Over 8.5 runs at 51¢ presents a 3.9% edge, with simulations resulting in a probability of 55.3%.

Giants +1.5 (+156)

• Edge: 3.7%
• Probability: 42.7%
• Matchup: Dodgers vs. Giants (4:05PM ET)

Our model finds value on Giants +1.5 at 39¢, supported by an edge of 3.7%.

Giants ML (+285)

• Edge: 3.5%
• Probability: 29.5%
• Matchup: Dodgers vs. Giants (4:05PM ET)

Our model has uncovered value on Dodgers-Giants to finish as a tie after 90 minutes at 26¢. A 29.5% probability produces a 3.5% edge, making this a strong play for today's MLB action.

Guardians vs. Royals Over 8.5 runs (+104)

• Edge: 3.4%
• Probability: 52.4%
• Matchup: Guardians vs. Royals (7:10PM ET)

A 3.4% edge on a 52.4% probability makes Over 8.5 runs at 49¢a solid value play in today's Guardians vs. Royals matchup.

Royals ML (+117)

• Edge: 3.4%
• Probability: 49.5%
• Matchup: Guardians vs. Royals (7:10PM ET)

Our model projects value on Royals to win at 46¢. A 49.5% probability produces a 3.4% edge, making Royals the favorable ML play in today's matchup.

Angels vs. Mariners Over 7.5 runs (-106)

• Edge: 3.1%
• Probability: 54.6%
• Matchup: Angels vs. Mariners (9:40PM ET)

Rounding out our top 10 bets, Angels vs. Mariners Over 7.5 runs at 51¢ shows a 54.6% probability and a 3.1% edge.

MLB best bets summary: Saturday, 9/26/2026

As of 3:08AM ET, here are our top MLB bets by edge recommended by our model:

List of upcoming MLB games to bet on [9/26/2026]

• Mets vs. Nationals (12:35PM ET, Saturday)
• Pirates vs. Tigers (1:10PM ET, Saturday)
• Reds vs. Blue Jays (3:07PM ET, Saturday)
• Dodgers vs. Giants (4:05PM ET, Saturday)
• Braves vs. Marlins (4:10PM ET, Saturday)
• Cardinals vs. Brewers (7:10PM ET, Saturday)
• Rockies vs. White Sox (7:10PM ET, Saturday)
• Guardians vs. Royals (7:10PM ET, Saturday)
• Angels vs. Mariners (9:40PM ET, Saturday)

Conclusion

Our MLB best bets are locked and loaded for September 26, 2026, featuring plays such as over 7.5 runs in the Reds vs. Blue Jays matchup and over 7.5 runs in the Dodgers vs. Giants matchup. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.