Phillies vs. Cardinals prediction: Philadelphia favored to win Monday's MLB matchup [8/10/2026]
Get Philadelphia Phillies vs St. Louis Cardinals predictions for MLB Monday.

The St. Louis Cardinals will take on the Philadelphia Phillies, in what is expected to be a close MLB game, at Busch Stadium on Monday, starting at 7:45 PM ET.
The Cardinals will start Hunter Dobbins (2-2, 3.60 ERA), pitting him against Andrew Painter (1-8, 6.48 ERA) for the Phillies.
Dimers' advanced MLB model gives the Phillies a slight edge with a 51.8% win probability over the Cardinals.
This article offers an expanded analysis of Monday's Phillies vs. Cardinals matchup, including best bets and picks.
Phillies vs. Cardinals prediction: Who will win and cover?
Our famous predictive model gives the Phillies a 51.8% chance of beating the Cardinals.
According to our model, the Cardinals (+1.5) have a 60.0% chance of covering the run line, while the over/under total of 8.5 runs has a 61.1% chance of going over,.
Phillies vs. Cardinals odds [8/10/2026]
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Phillies -1.5 (+150) / Cardinals +1.5 (-150)
- Moneyline: Phillies -105, Cardinals +108
All odds are correct at the time of publication and are subject to change.
Phillies vs. Cardinals picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Cardinals +1.5 @ -150 via DraftKings
- Moneyline: Phillies @ -105 via Bet365
- Total: Over 8.5 @ -127 via Novig
According to our best MLB bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Phillies vs. Cardinals game-day updates and essential details
Monday's MLB matchup between the Cardinals and Phillies at Busch Stadium is scheduled to begin at 7:45 PM ET.
- Who: Philadelphia Phillies vs. St. Louis Cardinals
- Date: Monday, August 10, 2026
- Time: 7:45 PM ET/4:45PM PT
- Venue: Busch Stadium
Conclusion
We predict the Phillies, with a 51.8% win probability, will likely beat the Cardinals in Monday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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