Jaguars vs. Broncos prediction favors Denver to win in NFL Week 2 [2026]

Since our Jaguars-Broncos predictions earlier in the week, we have re-simulated the result of Sunday's NFL game between the Jaguars and Broncos, forming part of our NFL predictions coverage.

Our independent predictive model gives the Broncos a 55.8% chance of beating the Jaguars in Week 2 of the NFL season. Our predicted final score has the Broncos winning 23-22.

Key factors favoring the Broncos:

• Denver Broncos Home Ground Advantage
• Denver Broncos Defensive Efficiency
• Denver Broncos Form

According to our model, the Jaguars (+2.5) have a 53.9% chance of covering the spread, while the over/under total of 45.5 points has an equal 50-50 chance of hitting.

To see win probabilities for every matchup this week, check out our expert NFL Week 2 straight up picks.

Latest betting odds

We have sourced the best NFL odds in America for this game, which are listed here:

• Spread: Jaguars +2.5 (+113) / Broncos -2.5 (-117)
• Moneyline: Jaguars +138, Broncos -144
• Total: Over/Under 45.5 (+102/-104)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Jaguars +2.5 @ 47¢ via Novig
• Moneyline: Jaguars @ 42¢ via Polymarket
• Total: Over 45.5 @ 50¢ via Novig

According to our NFL best bets, the top play to make on this game is Jaguars +2.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Jaguars vs. Broncos TD scorers

Who will score a touchdown in Jaguars vs. Broncos?

According to our model, J.K. Dobbins is most likely to score an anytime TD in Jaguars vs. Broncos.

Our projections give Dobbins a 40.1% chance of scoring a TD at Empower Field at Mile High, while the running back is a 9.3% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

Jacksonville Jaguars

• Bhayshul Tuten (RB): 34.5% probability
• Parker Washington (WR): 31.6%
• Chris Rodriguez (RB): 25.5%
• Trevor Lawrence (QB): 22.6%
• Jakobi Meyers (WR): 19.6%

Denver Broncos

• J.K. Dobbins (RB): 40.1% prob.
• Jaylen Waddle (WR): 29.6%
• RJ Harvey (RB): 28.6%
• Courtland Sutton (WR): 27.0%
• Bo Nix (QB): 20.0%

First touchdown scorer predictions

Jacksonville Jaguars

• Bhayshul Tuten (RB): 7.7% prob.
• Parker Washington (WR): 7.0%
• Chris Rodriguez (RB): 5.4%
• Trevor Lawrence (QB): 4.7%
• Jakobi Meyers (WR): 4.0%

Denver Broncos

• J.K. Dobbins (RB): 9.3% prob.
• Jaylen Waddle (WR): 6.4%
• RJ Harvey (RB): 6.1%
• Courtland Sutton (WR): 5.7%
• Bo Nix (QB): 4.1%

Top player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Jaguars and Broncos. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 2 games.

Quarterbacks

Of the starting quarterbacks, the Jaguars' Trevor Lawrence is projected for 232 passing yards, while the Broncos' Bo Nix is expected to throw for 229 yards.

Jaguars rushing

• Bhayshul Tuten: 50 yds
• Chris Rodriguez: 33 yds
• Trevor Lawrence: 21 yds

Broncos rushing

• J.K. Dobbins: 59 yds
• RJ Harvey: 26 yds
• Bo Nix: 21 yds

Jaguars receiving

• Parker Washington: 63 yds
• Jakobi Meyers: 43 yds
• Brian Thomas: 40 yds
• Brenton Strange: 35 yds
• Bhayshul Tuten: 13 yds

Broncos receiving

• Jaylen Waddle: 59 yds
• Courtland Sutton: 45 yds
• Pat Bryant: 37 yds
• Evan Engram: 27 yds
• RJ Harvey: 16 yds

Game info & kickoff details

The NFL Week 2 game between the Broncos and Jaguars at Empower Field at Mile High is scheduled to start at 4:05 PM ET.

• Who: Jacksonville Jaguars vs. Denver Broncos
• Date: Sunday, September 20, 2026
• Time: 4:05 PM ET/1:05PM PT
• Venue: Empower Field at Mile High

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Conclusion

We predict the Broncos, with a 55.8% win probability, will likely beat the Jaguars in Week 2 of the NFL season.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary NFL prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.