Los Angeles Rams vs. Denver Broncos: Experts release early Week 3 predictions [2026]

The Los Angeles Rams and Denver Broncos will meet in Week 3 of the NFL season at Empower Field at Mile High on Sunday, September 27, 2026, starting at 8:20 PM ET.

Initial simulations from Dimers' trusted NFL model favor the Rams as the most likely winner of this cross-conference clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Rams vs. Broncos predictions page.

LA Rams vs. Denver early predictions

Leveraging trusted machine learning and analysis, we have simulated the Rams vs. Broncos game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Rams 61.1%, Broncos 38.9%
• Predicted final score: Rams 23-20 Broncos
• Spread: Rams (-2.5) 54.6%, Broncos (+2.5) 45.4%
• Total points (45.5): Over 47.6%, Under 52.4%

As of September 21, 2026, these Rams-Broncos calculations and predictions reflect the latest data and insights available.

Rams vs. Broncos Week 3 details

Sunday's action between the Broncos and Rams at Empower Field at Mile High is scheduled for September 27, 2026.

• Who: Los Angeles Rams vs. Denver Broncos
• Date: Sunday, September 27, 2026
• Time: 8:20 PM ET/5:20PM PT
• Venue: Empower Field at Mile High

Rams vs. Broncos opening odds

We've researched the best betting odds across America for this Week 3 game, which are listed here:

• Spread: Rams -2.5 (-106), Broncos +2.5 (-105)
• Moneyline: Rams -127, Broncos +120
• Total: Over/Under 45.5 (-108/-108)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Rams, with a 61.1% win probability, will likely beat the Broncos in Week 3 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Rams vs. Broncos matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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