NFL best bets today: Week 2 picks include Jaguars vs. Broncos play [9/20/2026]

Today’s NFL picks for September 20, 2026 are here, with Jaguars vs. Broncos and Seahawks vs. Cardinals among the top plays identified by our model across Sunday’s NFL schedule.

Dimers’ predictive analytics engine runs 24/7, going over the latest football odds to uncover top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NFL best bets today [9/20, updated 3:35PM ET]

Below, you’ll find today’s NFL best bets, ranked by edge for Sunday, September 20, 2026.

Jaguars +2.5 (+113)

• Edge: 6.9%
• Probability: 53.9%
• Matchup: Jaguars vs. Broncos (4:05PM ET)

Our model has identified value on Jaguars +2.5 at 47¢ odds. A 53.9% probability produces an edge of 6.9%, making this the strongest play for today's NFL slate.

Cardinals +3.5 (+102)

• Edge: 5.7%
• Probability: 55.2%
• Matchup: Seahawks vs. Cardinals (4:25PM ET)

Cardinals +3.5 carries a 5.7% edge and a probability of 55.2% at 50¢ odds, according to our model.

Cardinals ML (+186)

• Edge: 3.8%
• Probability: 39.5%
• Matchup: Seahawks vs. Cardinals (4:25PM ET)

Cardinals ML at 35¢ odds shows a 3.8% edge, supported by a 39.5% probability in simulations.

Raiders +6.5 (+102)

• Edge: 2.9%
• Probability: 52.4%
• Matchup: Raiders vs. Chargers (4:05PM ET)

A 2.9% edge and 52.4% probability makes Raiders +6.5 vs. Chargers a value play in the Raiders vs. Chargers matchup, per our model.

Dolphins ML (+809)

• Edge: 2.5%
• Probability: 13.5%
• Matchup: Dolphins vs. 49ers (4:25PM ET)

Dolphins ML at 11¢ presents a 2.5% edge, with simulations resulting in a probability of 13.5%.

Jaguars ML (+138)

• Edge: 2.2%
• Probability: 44.2%
• Matchup: Jaguars vs. Broncos (4:05PM ET)

Our model finds value on Jaguars to win at 42¢, supported by an edge of 2.2%.

Raiders vs. Chargers Under 43.5 points (+100)

• Edge: 2.1%
• Probability: 52.1%
• Matchup: Raiders vs. Chargers (4:05PM ET)

Our model has uncovered value on Raiders vs. Chargers Under 43.5 points at 50¢. A 52.1% probability produces a 2.1% edge, making this a strong play for today's NFL action.

NFL best bets summary: Sunday, 9/20/2026

As of 3:35PM ET, here are our top NFL bets by edge recommended by our model:

List of upcoming NFL games to bet on [9/20/2026]

• Jaguars vs. Broncos (4:05PM ET, Sunday)
• Raiders vs. Chargers (4:05PM ET, Sunday)
• Seahawks vs. Cardinals (4:25PM ET, Sunday)
• Dolphins vs. 49ers (4:25PM ET, Sunday)
• Commanders vs. Cowboys (4:25PM ET, Sunday)
• Colts vs. Chiefs (8:20PM ET, Sunday)

See How Dimers Pro Enhances Your Best Bets

Discover the difference our best bets make with Dimers Pro. Check out this explainer video to see how you can gain an edge.

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Conclusion

Our NFL best bets are locked and loaded for September 20, 2026, featuring plays such as Jaguars +2.5 vs. Broncos and Cardinals +3.5. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.