Colorado vs. Baylor prediction favors Baylor to win in college football Week 4 [2026]

Baylor will face Colorado in Week 4 college football action at McLane Stadium on Saturday, with kickoff at 12:00 PM ET.

Dimers' advanced college football model projects Baylor as the most likely winner in this Colorado vs. Baylor prediction.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Colorado vs. Baylor prediction and odds

Using trusted machine learning and data, we have re-simulated the outcome of Colorado vs. Baylor, forming part of our college football predictions coverage.

Our famous predictive model currently gives Baylor a 78.3% chance of beating Colorado. Our predicted final score has Baylor winning 31-23. According to our model, Baylor (-8.5) has a 52.2% chance of covering the spread, while the over/under total of 55 points has a 52.4% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Colorado +8.5 (-110) / Baylor -8.5 (-105)
• Moneyline: Colorado +275, Baylor -320
• Total: Over/Under 55 (-110/-113)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Baylor -8.5 @ -105 via bet365
• Moneyline: Baylor @ -320 via bet365
• Total: Under 55 @ -113 via BetRivers

According to our college football best bets, the top play to make on this game is Baylor to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Baylor and Colorado at McLane Stadium is scheduled to begin at 12:00 PM ET.

• Who: Colorado vs. Baylor
• Date: Saturday, September 26, 2026
• Time: 12:00 PM ET/9:00AM PT
• Venue: McLane Stadium

College football Week 4 promos

Make the most of Dimers' Colorado vs. Baylor predictions by exploring the Bet365 Sportsbook offer below:

Conclusion

We predict Baylor, with a 78.3% win probability, will likely beat Colorado in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.