MLB picks today: Wednesday's MLB best bets include Red Sox vs. Yankees play [9/30/2026]
Get MLB picks today and best bets for Wednesday, September 30, 2026.

Today’s MLB picks for September 30, 2026 are here, with Red Sox vs. Yankees and Cubs vs. Padres among the top plays identified by our model across Wednesday’s MLB postseason slate.
Dimers’ predictive analytics engine runs 24/7, scanning the latest baseball odds to uncover legitimate betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of MLB best bets tonight [9/30, updated 6:34PM ET]
Below, you’ll find today’s MLB best bets, ranked by edge for Wednesday, September 30, 2026.
Red Sox vs. Yankees Over 6.5 runs (-115)
- Edge: 5.5%
- Probability: 59%
- Matchup: Red Sox vs. Yankees (8:00PM ET)
Our model has identified value on Over 6.5 runs in Red Sox vs. Yankees at 53¢ odds. A 59% probability produces an edge of 5.5%, making this the strongest play for today's MLB slate.
Cubs vs. Padres Over 7.5 runs (+113)
- Edge: 3.1%
- Probability: 50.1%
- Matchup: Cubs vs. Padres (10:00PM ET)
Cubs vs. Padres over 7.5 runs carries a 3.1% edge and a probability of 50.1% at 47¢ odds, according to our model.
MLB Playoffs best bets summary: Wednesday, 9/30/2026
As of 6:34PM ET, here are our top MLB bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Prob. |
|---|---|---|---|---|
| Red Sox vs. Yankees | Over 6.5 runs | 53¢ @ Novig | 5.5% | 59% |
| Cubs vs. Padres | Over 7.5 runs | 47¢ @ Polymarket | 3.1% | 50.1% |
List of upcoming MLB postseason games to bet on [9/30/2026]
- Red Sox vs. Yankees (8:00PM ET, Wednesday)
- Cubs vs. Padres (10:00PM ET, Wednesday)
Conclusion
Our MLB best bets are locked and loaded for September 30, 2026, featuring plays such as over 6.5 runs in the Red Sox vs. Yankees matchup and over 7.5 runs in the Cubs vs. Padres matchup. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are based on current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.



