Yankees vs. Diamondbacks prediction: Why Arizona is favored to win Sunday's MLB matchup [9/20/2026]

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Written by Dave Garofolo

Dimers' simulation model projects a 51.2% win probability for the Diamondbacks at Chase Field.

The New York Yankees take on the Arizona Diamondbacks in MLB action.
New York Yankees vs. Arizona Diamondbacks MLB prediction for Sunday, September 20, 2026.

MLB action continues on Sunday at 4:10 PM ET as the New York Yankees lock horns with the Arizona Diamondbacks at Chase Field.

Corbin Burnes (0-0, 5.87 ERA) will get the ball for the Diamondbacks, pitting him against Will Warren (10-6, 3.89 ERA) for the Yankees.

Dimers' proven MLB model gives the Diamondbacks a slight edge with a 51.2% win probability over the Yankees.

This article offers a complete Yankees vs. Diamondbacks prediction, including best bets and picks.

Yankees vs. Diamondbacks prediction and odds

Using powerful machine learning and statistical analysis, we have re-simulated the result of Sunday's MLB game between the Yankees and Diamondbacks, forming part of our MLB predictions coverage.

Our independent predictive model gives the Diamondbacks a 51.2% chance of defeating the Yankees. According to our model, the Diamondbacks (+1.5) have a 63.4% chance of covering the run line, while the 8.5-run over/under has a 54.5% chance of going over.

 

Latest betting odds

We have sourced the best MLB odds in America for this game, which are listed here:

  • Run Line: Yankees -1.5 (+156) / Diamondbacks +1.5 (-156)
  • Moneyline: Yankees -108, Diamondbacks +104
  • Total: Over/Under 8.5 (+104/-106)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

  • Run line: Diamondbacks +1.5 @ 61¢ via Novig
  • Moneyline: Diamondbacks @ 49¢ via Novig
  • Total: Over 8.5 @ 49¢ via Polymarket

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first pitch details

Sunday's MLB action between the Diamondbacks and Yankees at Chase Field is scheduled to begin at 4:10 PM ET.

Conclusion

We predict the Diamondbacks, with a 51.2% win probability, will likely beat the Yankees in Sunday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary MLB prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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