Broncos vs. Cardinals prediction: Why Denver is favored to win in NFL Week 7 [2026]

Since our Broncos-Cardinals predictions earlier in the week, we have re-simulated the outcome of Sunday's NFL game between the Broncos and Cardinals, forming part of our NFL predictions coverage.

Our leading predictive model gives the Broncos a 63.7% chance of defeating the Cardinals in Week 7 of the NFL season. Our predicted final score has the Broncos winning 23-19.

Key factors favoring the Broncos:

• Broncos team rating
• Cardinals defense
• Cardinals recent performance

According to our model, the Cardinals (+4.5) have a 51.7% chance of covering the spread, while the over/under total of 43.5 points has an equal 50-50 chance of hitting.

To see win probabilities for every matchup this week, check out our expert NFL Week 7 straight up picks.

Latest betting odds

We have sourced the best NFL odds in America for this game, which are listed here:

• Spread: Broncos -4.5 (-102) / Cardinals +4.5 (+100)
• Moneyline: Broncos -212, Cardinals +203
• Total: Over/Under 43.5 (+104/-108)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Cardinals +4.5 @ 50¢ via Novig
• Moneyline: Cardinals @ 33¢ via Novig
• Total: Over 43.5 @ 49¢ via Novig

According to our NFL best bets, the top play to make on this game is Cardinals to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Broncos vs. Cardinals TD scorers

Who will score a touchdown in Broncos vs. Cardinals?

According to our list of touchdown scorer predictions for Week 7, Trey McBride is most likely to score an anytime TD in Broncos vs. Cardinals.

Our projections give McBride a 38.1% chance of scoring a TD at State Farm Stadium, while the tight end is a 10.1% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

Denver Broncos

• J.K. Dobbins (RB): 35.1% probability
• Jaylen Waddle (WR): 29.5%
• RJ Harvey (RB): 28.4%
• Courtland Sutton (WR): 26.3%
• Evan Engram (TE): 18.6%

Arizona Cardinals

• Trey McBride (TE): 38.1% prob.
• Tyler Allgeier (RB): 30.3%
• Michael Wilson (WR): 28.7%
• Bam Knight (RB): 27.2%
• Kendrick Bourne (WR): 15.9%

First touchdown scorer predictions

Denver Broncos

• J.K. Dobbins (RB): 8.2% prob.
• Jaylen Waddle (WR): 6.7%
• RJ Harvey (RB): 6.4%
• Courtland Sutton (WR): 5.8%
• Evan Engram (TE): 3.9%

Arizona Cardinals

• Trey McBride (TE): 10.1% prob.
• Tyler Allgeier (RB): 7.6%
• Michael Wilson (WR): 7.1%
• Bam Knight (RB): 6.7%
• Kendrick Bourne (WR): 3.6%

Top player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Broncos and Cardinals. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 7 games.

Quarterbacks

Of the starting quarterbacks, the Broncos' Bo Nix is projected for 224 passing yards, while the Cardinals' Jacoby Brissett is expected to throw for 232 yards.

Broncos rushing

• J.K. Dobbins: 56 yds
• RJ Harvey: 22 yds
• Jonah Coleman: 18 yds

Cardinals rushing

• Bam Knight: 39 yds
• Tyler Allgeier: 34 yds
• Jacoby Brissett: 11 yds

Broncos receiving

• Jaylen Waddle: 57 yds
• Courtland Sutton: 40 yds
• RJ Harvey: 27 yds
• Evan Engram: 26 yds
• Troy Franklin: 22 yds

Cardinals receiving

• Trey McBride: 62 yds
• Michael Wilson: 55 yds
• Kendrick Bourne: 39 yds
• Jalen Brooks: 23 yds
• Elijah Higgins: 16 yds

Game info & kickoff details

The NFL Week 7 action between the Cardinals and Broncos at State Farm Stadium is scheduled to commence at 4:05 PM ET.

• Who: Denver Broncos vs. Arizona Cardinals
• Date: Sunday, October 25, 2026
• Time: 4:05 PM ET/1:05 PM PT
• Venue: State Farm Stadium

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Conclusion

We predict the Broncos, with a 63.7% win probability, will likely beat the Cardinals in Week 7 of the NFL season.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary NFL prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.