Colts vs. Vikings prediction: Why Minnesota is favored to win in NFL Week 7 [2026]

Since our Colts-Vikings predictions earlier in the week, we have re-simulated the outcome of Sunday's NFL matchup between the Colts and Vikings, forming part of our NFL predictions coverage.

Our leading predictive model currently gives the Vikings a 72.0% chance of defeating the Colts in Week 7 of the NFL season. Our predicted final score has the Vikings winning 25-18.

Key factors favoring the Vikings:

• Vikings team rating
• Vikings QB situation
• Colts QB situation

According to our model, the oddsmakers have got it right, and the Colts and Vikings each have a 50% chance of covering the spread, while the 42.5-point over/under has a 54.0% chance of going over.

Here's what's driving the over's higher probability::

• Playing conditions
• Vikings recent performance

To see win probabilities for every matchup this week, check out our expert NFL Week 7 straight up picks.

Latest betting odds

We have sourced the best NFL odds in America for this game, which are listed here:

• Spread: Colts +6.5 (+106) / Vikings -6.5 (-108)
• Moneyline: Colts +270, Vikings -285
• Total: Over/Under 42.5 (+113/-117)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Colts +6.5 @ 49¢ via Novig
• Moneyline: Colts @ 27¢ via Novig
• Total: Over 42.5 @ 47¢ via Polymarket

According to our NFL best bets, the top play to make on this game is Over 42.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Colts vs. Vikings TD scorers

Who will score a touchdown in Colts vs. Vikings?

According to our model, Jonathan Taylor is most likely to score an anytime TD in Colts vs. Vikings.

Our projections give Taylor a 55.3% chance of scoring a TD at U.S. Bank Stadium, while the running back is a 16.8% chance of registering the first touchdown the game.

Anytime touchdown scorer predictions

Indianapolis Colts

• Jonathan Taylor (RB): 55.3% probability
• Keenan Allen (WR): 18.0%
• Josh Downs (WR): 16.0%
• Will Mallory (TE): 12.3%
• Daniel Jones (QB): 10.8%

Minnesota Vikings

• Aaron Jones (RB): 39.3% prob.
• Jordan Mason (RB): 37.9%
• Justin Jefferson (WR): 36.9%
• T.J. Hockenson (TE): 25.2%
• Jordan Addison (WR): 24.4%

First touchdown scorer predictions

Indianapolis Colts

• Jonathan Taylor (RB): 16.8% prob.
• Keenan Allen (WR): 4.1%
• Josh Downs (WR): 3.6%
• Will Mallory (TE): 2.7%
• Daniel Jones (QB): 2.4%

Minnesota Vikings

• Aaron Jones (RB): 9.9% prob.
• Jordan Mason (RB): 9.5%
• Justin Jefferson (WR): 9.2%
• T.J. Hockenson (TE): 5.8%
• Jordan Addison (WR): 5.6%

Top player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Colts and Vikings. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 7 games.

Quarterbacks

Of the starting quarterbacks, the Colts' Daniel Jones is projected for 200 passing yards. The Vikings' Kyler Murray is expected to throw for 213 yards.

Colts rushing

• Jonathan Taylor: 73 yds
• Seth McGowan: 17 yds
• Daniel Jones: 12 yds

Vikings rushing

• Jordan Mason: 53 yds
• Aaron Jones: 46 yds
• Kyler Murray: 28 yds

Colts receiving

• Josh Downs: 54 yds
• Keenan Allen: 48 yds
• Laquon Treadwell: 26 yds
• Will Mallory: 24 yds
• Jonathan Taylor: 20 yds

Vikings receiving

• Justin Jefferson: 76 yds
• Jordan Addison: 44 yds
• T.J. Hockenson: 41 yds
• Aaron Jones: 18 yds
• Jauan Jennings: 15 yds

Game info & kickoff details

The NFL Week 7 matchup between the Vikings and Colts at U.S. Bank Stadium is scheduled to commence at 1:00 PM ET.

• Who: Indianapolis Colts vs. Minnesota Vikings
• Date: Sunday, October 25, 2026
• Time: 1:00 PM ET/10:00 AM PT
• Venue: U.S. Bank Stadium

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Conclusion

We predict the Vikings, with a 72.0% win probability, will likely beat the Colts in Week 7 of the NFL season.

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This article's predictions and probabilities are generated by Dimers' proprietary NFL prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.