NFL picks straight up: Week 8, 2026

At Dimers, our Week 8 NFL picks are grounded in data-driven insight, with straight-up picks for all 14 games informed by our latest NFL predictions.

Get an advantage in your NFL pick 'em competitions via our data-driven NFL Week 8 picks straight up, powered by thousands of game simulations.

Week 8 of the NFL season begins with the Carolina Panthers facing the Green Bay Packers on Thursday night and concludes with the Chicago Bears taking on the Seattle Seahawks on Monday.

NFL picks this week straight up: Week 8, 2026

Here are our Week 8 NFL picks highlighting how likely each team is to win their game this week.

Carolina Panthers vs. Green Bay Packers

The Panthers kick off Week 8 against the Packers at Lambeau Field on Thursday night. According to our NFL model, the Packers have a 64% chance of winning, while the Panthers have a 36% chance.

For Week 8's opening game, our model highlights NFL player projections, with Chuba Hubbard (RB) the most likely player from the Panthers to score the first TD at 12.2%, while Josh Jacobs (RB) is the top candidate from the Packers at 13.7%.

Check out our full Carolina Panthers vs. Green Bay Packers prediction ahead of this week's matchup at Lambeau Field, set for Thursday, October 29 at 8:15pm. All times stated in this article are in Eastern Standard Time (EST).

Indianapolis Colts vs. Jacksonville Jaguars

For this week's game between the Colts and the Jaguars, Jacksonville is more likely to win. Our prediction model gives the Jaguars an 80% chance of winning. On the other hand, there is a 20% chance that the Colts will pull off an upset win.

Explore the latest data in this week's Indianapolis Colts vs. Jacksonville Jaguars prediction before kickoff in Jacksonvilleon Sunday at 1:00pm.

As the regular season approaches its conclusion, track the top teams with our updated NFL futures, highlighting top Super Bowl contenders.

Tennessee Titans vs. Cincinnati Bengals

We are picking the Bengals to win their game against the Titans this week, with our powerful NFL model projecting an 84% win probability for the home team. The Titans have a 16% chance of winning at Paycor Stadium.

For betting purposes, the Bengals are listed as -11 favorites, with the Titans' moneyline at +500.

Find the complete Tennessee Titans vs. Cincinnati Bengals prediction for a closer look at Sunday's 1:00pm game.

Cleveland Browns vs. Pittsburgh Steelers

According to our predictive analytics model, the Steelers are the team to beat in this game, with their win probability at 64%. The Browns, on the other hand, have a 36% chance of winning.

Review the edges and numbers in our Cleveland Browns vs. Pittsburgh Steelers prediction for this Sunday 1:00pm clash at Acrisure Stadium.

Minnesota Vikings vs. Detroit Lions

The Lions have a 62% chance of winning on Sunday afternoon, compared to the Vikings' 38% chance of victory. This makes the Detroit Lions our pick to win at Ford Field.

See the numbers behind this matchup in the full Minnesota Vikings vs. Detroit Lions prediction scheduled for Sunday at 1:00pm at Ford Field.

Atlanta Falcons vs. Tampa Bay Buccaneers

The Buccaneers are favorites to win this game, with our predictive analytics model giving them a 58% chance, while the Falcons enter the weekend with a 42% chance of winning at Raymond James Stadium.

When it comes to betting on this game, the Falcons' moneyline odds are set at +120, with the home team Buccaneers listed as -2.5 favorites.

This week's Atlanta Falcons vs. Tampa Bay Buccaneers prediction highlights the top values for the game at Raymond James Stadium on Sunday, November 1 at 1:00pm.

Arizona Cardinals vs. Dallas Cowboys

After 10,000 simulations of Cardinals vs. Cowboys this Sunday, our model projects the Cowboys as the more likely winners with a probability of 73%. Their opponents, the Cardinals, have a 27% chance of getting the win on the road.

Compare projections and odds for this matchup in our Arizona Cardinals vs. Dallas Cowboys prediction, set for Sunday at 1:00pm.

Las Vegas Raiders vs. New York Jets

Our model is picking the Jets, who have a 59% chance of winning the matchup, while the Raiders have a 41% win probability.

Access the full data breakdown in our Las Vegas Raiders vs. New York Jets prediction ahead of kickoff at MetLife Stadium.

Baltimore Ravens vs. Buffalo Bills

The next game of Week 8 sees the Ravens take on the Bills at Highmark Stadium.

We predict the Bills to win with a probability of 60%, while the Ravens are projected to have a win chance of 40%.

As for the Vegas betting odds here, the Bills are listed as -3 favorites, with the Ravens' moneyline odds posted at +142.

Breakdown further probabilities and player projections in the Baltimore Ravens vs. Buffalo Bills prediction for Sunday, November 1 at 1:00pm.

Los Angeles Chargers vs. Los Angeles Rams

The likely winner of this matchup is the Rams, who have a projected win chance of 74%, according to DimersBOT. On the other side of this matchup, the Chargers have a projected win probability of 26%.

Check out our Los Angeles Chargers vs. Los Angeles Rams prediction to see where the rest of the numbers lean ahead of Sunday's game in Los Angeles.

New England Patriots vs. Miami Dolphins

We have run our powerful NFL model over this week’s Patriots-Dolphins clash 10,000 times, with the Patriots coming out as the team to pick. Of those 10,000 simulations, the Patriots won 7,211 times, with the Dolphins winning on 2,789 occasions.

Get direct access to more game projections with our New England Patriots vs. Miami Dolphins prediction before Sunday's clash at Hard Rock Stadium

Kansas City Chiefs vs. Denver Broncos

Next up is the game between the Chiefs and Broncos, with our model projecting the road team as the more likely victor, with the Chiefs rated as having a 58% chance of getting the W. The Broncos, on the other hand, are projected to have a 42% chance of winning.

For those interested in betting on this matchup, the oddsmakers have the Chiefs' moneyline odds set at -118 for this road game, while the hosting Broncos are listed as +1.5 underdogs.

Examine further probabilities in the full Kansas City Chiefs vs. Denver Broncos prediction, scheduled for Sunday at 4:25pm.

Philadelphia Eagles vs. Washington Commanders

Our next straight up pick this week is for the Commanders to get the win against the Eagles. After running 10,000 simulations of this matchup, the Washington have a win probability of 71%, with the Eagles at 29%.

View the complete Philadelphia Eagles vs. Washington Commanders prediction for a deeper look at this Sunday's game in Washington.

Chicago Bears vs. Seattle Seahawks

With a win probability of 61% on Monday night, our straight up pick for this game is the Seahawks, while their opponent, the Bears, have a projected win chance of 39%.

Check out the latest projections in this week's Chicago Bears vs. Seattle Seahawks prediction before kickoff on Monday, November 2 at 8:15pm.

Full list of NFL Week 8 picks straight up

This week's most likely NFL winners, ordered by probability:

• Bengals 84.0% vs. Titans
• Jaguars 79.7% vs. Colts
• Rams 74.4% vs. Chargers
• Cowboys 72.5% vs. Cardinals
• Patriots 72.1% @ Dolphins
• Commanders 70.8% vs. Eagles
• Packers 64.2% vs. Panthers
• Steelers 63.8% vs. Browns
• Lions 61.9% vs. Vikings
• Seahawks 60.6% vs. Bears
• Bills 60.3% vs. Ravens
• Jets 58.6% vs. Raiders
• Buccaneers 58.2% vs. Falcons
• Chiefs 57.5% @ Broncos

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NFL straight up picks and predictions for Week 8

The NFL Week 8 predictions straight up in this article are accurate at the time of publication but may change.

Dimers.com is the best site for NFL predictions, with our straight up picks trusted by football fans across the country.

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Please note that all NFL odds and probabilities mentioned on this page are subject to change.