South Carolina State vs. Howard prediction favors South Carolina State to win in college football Week 10 [2026]

Using powerful machine learning and data, we have re-simulated the result of South Carolina State vs. Howard, forming part of our college football predictions coverage.

Our independent predictive model gives South Carolina State a 91.7% chance of beating Howard. Our predicted final score has South Carolina State winning 33-13. According to our model, Howard (+20.5) has a 52.9% chance of covering the spread, while the 50.5-point over/under has a 58.9% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: South Carolina State -20.5 (-111) / Howard +20.5 (-109)
• Moneyline: South Carolina State -1011, Howard +953
• Total: Over/Under 50.5 (+156/-178)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Howard +20.5 @ -109 via Caesars
• Moneyline: South Carolina State @ 91¢ via Novig
• Total: Over 50.5 @ 39¢ via Novig

According to our college football best bets, the top play to make on this game is Over 50.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Thursday's college football game between Howard and South Carolina State at William H. Greene Stadium is scheduled to start at 7:30 PM ET.

• Who: South Carolina State vs. Howard
• Date: Thursday, November 5, 2026
• Time: 7:30 PM ET/4:30 PM PT
• Venue: William H. Greene Stadium

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Conclusion

We predict South Carolina State, with a 91.7% win probability, will likely beat Howard in Thursday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary college football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.