Inter Miami vs. FC Cincinnati prediction, odds, MLS Cup first round picks [10/28/2026]

Miami and Cincinnati are scheduled to meet in the MLS Cup first round at Nu Stadium on Wednesday, with kickoff at 7:30 PM ET.

Dimers' advanced MLS model projects Miami as the most likely winner in this Miami vs. Cincinnati prediction.

This article offers a closer look at Wednesday's match, including best bets and picks.

Inter Miami vs. FC Cincinnati prediction and odds

Using innovative machine learning and data, we have re-simulated the result of Wednesday's MLS game between Miami and Cincinnati, forming part of our MLS predictions coverage.

Our leading predictive model currently suggests a 68.8% chance of Miami winning, a 16.1% chance for Cincinnati, and a 15.1% chance of a draw. Additionally, the over/under total of 2.5 goals has a 84.3% chance of going over., according to our model.

Latest betting odds

We have sourced the best MLS odds in America for this game, which are listed here:

• Moneyline: Cincinnati +500, Miami -199
• Total Goals: Over/Under 2.5 (-400/+355)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet for MLS Cup first round

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Miami @ -199 via Kalshi
• Total Goals: Over 2.5 @ -400 via Polymarket

According to our best MLS bets, the top play to make on this game is Over 2.5 total goals.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score projections

The top three most likely final scores, according to our model, are listed below, with a 3-1 Miami win being the most probable:

• Miami 3-1 Cincinnati (7.3% probability)
• Miami 2-1 Cincinnati (7%)
• Miami 5-1 Cincinnati (6.9%)

Game info & kickoff details

Wednesday's MLS game between Miami and Cincinnati in MLS at Nu Stadium is scheduled to begin at 7:30 PM ET.

• Who: Inter Miami vs. FC Cincinnati
• Date: Wednesday, October 28, 2026
• Time: 7:30 PM ET/4:30 PM PT
• Venue: Nu Stadium

Conclusion

According to our computer model, Miami has a 68.8% win probability on Wednesday, Cincinnati has a 16.1% win probability, and there is a 15.1% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary MLS prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.