NFL best bets today: Week 18 picks highlight Seahawks vs. 49ers play [1/3/2026]

Updated: January 3, 2026, 4:04 PM ET | First published: January 3, 2026, 12:05 AM ET

Written by Ryan Leaver, Senior Editor

Get NFL best bets and predictions for Saturday, January 3, 2026.

Today’s NFL picks for January 3, 2026 are here, with Seahawks vs. 49ers among the top plays identified by our model across Saturday’s NFL play.

Dimers’ predictive analytics engine runs 24/7, searching the latest football odds to find real betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NFL best bets tonight [1/3, updated 4:04PM ET]

Below, you’ll find today’s best football bets, ranked by edge for Saturday, January 3, 2026.

49ers +2.5 (-105)

Edge: 7.0%
Probability: 58.2%
Matchup: Seahawks vs. 49ers (8:00PM ET, Saturday)

Our model has identified value on 49ers +2.5 at -105 odds. A 58.2% probability produces an edge of 7.0%, making this the strongest play for today's NFL slate.

NFL best bets summary: Saturday, 1/3/2026

As of 4:04PM ET, here is our top NFL bet by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Seahawks vs. 49ers	49ers +2.5	-105 @ DraftKings	7.0%	58.2%

List of upcoming NFL games to bet on [1/3/2026]

Panthers vs. Buccaneers (4:30PM ET, Saturday)
Seahawks vs. 49ers (8:00PM ET, Saturday)
Packers vs. Vikings (1:00PM ET, Sunday)
Titans vs. Jaguars (1:00PM ET, Sunday)
Colts vs. Texans (1:00PM ET, Sunday)
Cowboys vs. Giants (1:00PM ET, Sunday)
Browns vs. Bengals (1:00PM ET, Sunday)
Saints vs. Falcons (1:00PM ET, Sunday)

AI betting support with Dimebot

Learn how Dimebot uses Dimers’ data to deliver quick answers and insights, helping you make faster, more informed decisions.

NFL betting promos for Week 18

Make the most of our best bets today—including 49ers +2.5—with the two offers listed below.

DraftKings Sportsbook

Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $200 in bonus bets win or lose.

Conclusion

Our NFL best bets are locked and loaded for January 3, 2026, featuring plays such as 49ers +2.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate NFL insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.

Written by

Ryan Leaver

Senior Editor

Ryan Leaver specializes in sports betting analysis across the NBA, NFL, college football, college basketball, and soccer. Drawing on advanced statistical models, simulations, and historical data, he produces game previews, betting picks, player prop analysis, and futures coverage to help bettors make more informed decisions.

Advertiser disclosure